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4.1.4 Therapeutic targeting of ferroptosis in ischemic stroke The primary goal in treating ischemic stroke is rapid reperfusion, a prerequisite for effective neuroprotection

Caccuri F, Bugatti A, Zani A, De Palma A, Di Silvestre D, Manocha E, et al

Non-human primates (NHPs), such as rhesus monkeys, naturally exhibit age related tau and amyloid (A) pathologies, providing models that closely mimic human disease progression (Li et al., 2019)

However, if the goal is to study systemic effectslike tendon repair, muscle recovery, or neuroprotectiona higher dose might be necessary to ensure enough of the compound survives the digestive gauntlet and reaches the bloodstream to circulate throughout the body