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The oxidative degradation mechanism is depicted in Figure 3C, where H 2 O 2 triggers the breakdown of GO@GSH-FA by detaching the phenylboronic acid derivative, leading to the accelerated release of the GSH

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Nrf2 plays an important role in neurodegeneration and ferroptosis by regulating a wide range of genes (Song and Long, 2020)

These factors make drug development a very challenging task