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Furthermore, IL-6 stimulates angiogenesis through the upregulation of VEGF, further supporting tumor growth and metastasis [133]

Yendamuri S, Vaporciyan AA, Zaidi T, Feng L, Fernandez R, Bekele NB, Hofstetter WL, Jiang F, Mehran RJ, Rice DC, Spitz MR, Swisher SG , Walsh GL, Roth JA, Katz RL