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Exclusion criteria were: diabetes, cardiovascular disorders, beta blockers treatment, morbid obesity, thyroid disorders, post-radical prostatectomy, and hepatic/renal failure

The hydroxyl free radicals produced due to participation of iron are highly reactive

4.4 Sedative Hypnotics Clinically significant drug interactions between sedative hypnotics and COVID-19 agents, especially with ritonavir-boosted PIs, were documented in healthy volunteers and in patients without COVID-19