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used the Mannich condensation reaction between the antioxidant selenomethionine and EGCG to efficiently synthesize a polyphenol-based nanomedicine (ES NDs) in an aqueous medium for OA treatment

To determine if IL-1 undergoes K48-linked ubiquitylation and/or is modified with other ubiquitin linkage types, ubiquitylated IL-1 was isolated from macrophages stimulated with LPS and MG132 and subjected to treatment with deubiquitinating enzymes specific for K63-linked (AMSH), K48-linked (OTUB1), K11-linked (Cezanne), and M1 linear-linked (OTULIN) ubiquitin chains (Fig

2014;26(10):1729-1735 Wennberg AMV

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