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7.3.4 Molecular imaging markers based on 5-hydroxytryptaminergic and glutamatergic systems Non-dopaminergic biomarkers may enable the detection of pathologic alterations associated with PD in stages 12, in case of involvement of dopaminergic neurons in PD, or Braak 3

These include the complex composition of compound formulations, the challenging identification of quality control indicators, and the difficulty in establishing pharmacokinetic methods in vivo [171]