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The purified DNA was digested into component nucleotides using nuclease P 1 , snake venom phosphodiesterase and alkaline phosphatase as previously described in detail

A univariate analysis of variance (ANOVA) was used to determine whether the relative abundance of each identified metabolite was significantly different between wild-type and mutant strains under each growth condition

Although several studies have demonstrated the efficacy of RSL3 in various animal models ( in vivo ( To date, the majority of studies regarding drug-tolerant persister cells have focused on persister cells from immortalized cell lines, demonstrating that they occur as a small subset of the total tumor population ( In summary, we studied the characteristics of CRC DTP cells derived from the chemotherapy or targeted agents, and the effects of ferroptosis on persister cells

Identification and Successful Negotiation of a Metabolic Checkpoint in Direct Neuronal Reprogramming