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PLoS One (2014) 9:e104762

-LYASE AND GENERATION OF CYTOTOXIC PRODUCTS Cysteine conjugates produced by dipeptidases or amino peptidases following the GST and GT steps, are transformed by cysteine conjugate -lyases present in the cytosol and mitochondria

Also, point mutations in DEC2 , a clockwork gene for biological time, have been found among humans who are short sleepers, and mice with DEC2 mutations have shown the same decrease in sleep time 24

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