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Apolipoprotein E deficiency activates thermogenesis of white adipose tissues in mice through enhancing beta-hydroxybutyrate production from precursor cells

It was developed at Monash University in Australia and taken through clinical work in the early 2000s as an obesity research candidate

research-amq-06 Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice

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