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Due to the peptide compositions, AMPs are unfortunately limited in their potential to be used in vivo by a number of variables, including minimal tissue penetration, rapid removal from circulation, decreased bioavailability, limited stability, and low selectivity against bacterial cells relative to mammalian cells

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Hurst R, Bao Y, Jemth P, Mannervik B, Williamson G

Depending on the treatment plan, trastuzumab may be initiated immediately after diagnosis (as with TCH regimens Docetaxel, Carboplatin, and Trastuzumab or similar regimens), following surgical procedures (as with trastuzumab monotherapy or trastuzumab combined with taxanes), or after the start of adjuvant therapy (as with ACTH regimensDoxorubicin, Cyclophosphamide, Taxol, and Trastuzumab or similar regimens) 55