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While this concern comes largely from human medicine rather than strong equine evidence, it is still a reasonable precaution

[DOI] [PMC free article] [PubMed] [Google Scholar] 680.Rustenhoven J, et al

Stimulation of guanylate cyclase by sodium nitroprusside, nitroglycerin and nitric oxide in various tissue preparations and comparison to the effects of sodium azide and hydroxylamine