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doi:10.1002/14651858.CD002025.pub5 Santo Jr T, Clark B, Hickman M, et al

Diabetic patients with conventional subcutaneous insulin therapy had lower IGF-1 levels than patients with continuous subcutaneous insulin infusion and intraportal insulin infusion [13]

2 Recent advancements in NDDS for CRC treatment 2.1 Oral drug delivery systems Oral administration is a preferred route for drug delivery due to its non-invasiveness, patient compliance, and suitability for both local and systemic therapies (Liu et al., 1997)