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FIGURE 3 TPPU and DHA + TPPU Decrease Inflammation in the Hippocampus of Diabetic Rats An increase in the neuroinflammation was evident in the hippocampus of diabetic rats due to the rise in the level of pro-inflammatory marker IL-1 (Figure 4A) (412 29 pg/ml) and IL-6 (Figure 4B) (180 6 pg/ml) and decrease in the level of anti-inflammatory marker IL-10 (Figure 4C) (220 7 pg/ml) in comparison to the healthy normal rats (IL-1, 311 14 pg/ml

Melatonin also has antioxidant properties and antitumor and immune-modulating effects

The continuous introduction of new drugs and clinical trials has significantly improved patient survival outcomes