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[DOI] [PubMed] [Google Scholar] 108.Foxton R.H., Land J.M., Heales S.J.R

10.1038/nature09623 141

This rapid clearance may help prevent the toxic accumulation of mediators in the bloodstream, significantly reducing the severity and duration of systemic MCAS flares, such as flushing, gastrointestinal distress, and neurological inflammation