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plantarum , the regulation network of CopR was summarized in Figure 9

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Importantly, the majority of studies in this area used the oversimplistic M1 and M2 macrophage classifications, whereas in recent years advancements have been made to study the more elaborate classifications of macrophages in the general immunology setting 90 , and this should thus be applied to the macrophages in wound healing setting 91

Note that from the above studies, it is likely that upregulation of these antioxidants is muscle- and/or fiber type-specific