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Although relatively small in scale, First-in-Human trials generate several key insights that guide later clinical development.

Excessive NMDA activation contributes to excitotoxicity during and after stroke, making NMDA modulation a potential therapeutic target

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The review confirmed that GHK-Cu stimulates blood vessel and nerve outgrowth, increases collagen, elastin, and glycosaminoglycan synthesis, and supports dermal fibroblast function