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10.1016/j.jtcvs.2014.09.062 12 Jorge-HerreroE.FernndezP.EscuderoC.Garca-PezJ

Structural basis for CDK7 activation by MAT1 and cyclin H

Consequently, the suggested combination approach holds the promise of enabling the use of lower doses of conventional chemotherapy, thereby mitigating undesirable toxic effects