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The mean change in homocysteine levels was greater (-3.2 m/L vs -1.1 m/L) in patients with higher homocysteine baseline levels (mean, 15.6 m/L) than in those with lower levels (mean, 8.0 m/L)

Reduced insulin-mediated citrate synthase activity in cultured skeletal muscle cells from patients with type 2 diabetes: evidence for an intrinsic oxidative enzyme defect