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these medications interfere with the structure and function of the HIV capsid and thereby block multiple steps in the HIV lifecycle pathway (Figure 17).[52] Lenacapavir is the only drug in this class that has been approved by the FDA

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Clinical and in vivo PD studies using repurposed anti-diabetic medications report mixed results but suggest an overall potential modest benefit (50) in motor and cognitive symptoms with GLP-1 receptor agonists taken for at least 12 months (51)