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Grk6 knockdown reduces cellular insulin levels, and attenuates insulin secretion, but enhances proinsulin secretion consistent with decreased processing [138]

Ukr Khim Zh 22:603607 Pfeffer MA, Braunwald E, Moy LA, Basta L, Brown EJ Jr, Cuddy TE, Davis BR, Geltman EM, Goldman S, Flaker GC et al (1992) Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction: results of the Survival and Ventricular Enlargement Trial

In addition to the psychotropic effects (due to the activation of the CNS CB1 receptor), THC by acting on CNS CB1: (1) Induces drowsiness and impairment of short term memory