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The antioxidant activity is especially critical for the operation of glutathione peroxidase (GPx), an enzyme that catalyzes the reduction of peroxides using GSH as an electron donor, oxidizing it to its disulfide form, GSSG (glutathione disulfide)

Doses under 1200mg can be given as a single shot and doses over 1200mg will need to be given as an infusion

Body temperature was not significantly affected by infection in this model

The directionality of this relationship is debated: low testosterone may cause metabolic dysfunction, metabolic dysfunction may suppress testosterone, or both may be downstream of common upstream causes