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76,77 Decreased MAT activity is attributable to alcohol-induced oxidative stress and reactive aldehydes, which can inactivate the liver-specific MAT

Boukouris AE, Zervopoulos SD, Michelakis ED

In addition to tumor growth and angiogenesis, hexavalent chromium-transformed cells also presented a 35-fold decrease in the expression of miR-143, a crucial regulator of IGF-IR/IRS1 signaling (He et al

System Xc- is a heterodimeric complex composed of the light chain SLC7A11 and the heavy chain SLC3A2, which mediates the 1:1 exchange of extracellular cystine for intracellular glutamate (Figure 2)