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It helps eliminate toxins and harmful substances from the body, promoting the proper functioning of detoxification organs such as the liver and kidneys

With respect to epigenetic regulation, CTBP functions as a transcriptional repressor by associating with nucleosome remodeling and the deacetylase (NURD) complex 148 , class II HDACs (HDAC4/5/7/9) 178 , and COREST (co-repressor of REST), which includes HDAC1/2 and LSD1, and removes acetyl groups and H3K4 monomethylation/dimethylation from nucleosomes, leading to transcriptional repression 179 (Fig

J Cancer Res Clin Oncol (2009) 135(9):12239

Funding This research was supported by Luzhou's major scientific and technology research and development project (nos.2022-SYF-42), Luzhou Municipal People's GovernmentSouthwest Medical University Science and Technology Strategic Cooperation Climbing Plan Project, (2021LZXNYD-D02), Joint Innovation Special of the Sichuan Provincial Science and Technology Plan (nos.2022YFS0609/2022YFS0609-B3), the Sichuan Science and Technology Department Project Development Project(nos