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In fact, even though autoantibodies are produced by B cells, it is well known now that T cells critically participate in the pathogenesis of SLE because of their ability to guide B cells in autoantibody production

major improvement in energy levels, skin smoothness, inflammation is definitely better

Mechanistically, phenotypic heterogeneity may arise from factors such as uneven division of cells and their constituents, heterogeneous stages of the cell cycle or cell ageing, epigenetic modifications and stochastic gene expression [111314]

However, as the injury persists, autophagy is over-activated, which subsequently triggers apoptosis, inducing cell death and ultimately aggravating brain injury