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Although included patients in two groups were thoroughly selected

In older children with mild disease, a 1 mg daily oral treatment regimen is suggested ( The different recommended doses, formulations and treatment schedules both between and within these countries highlight the important disparity in international clinical practice for the treatment of this heterogenous condition

Retention of misfolded TYR proteins in the endoplasmic reticulum results in the loss of pigmentation, which has also been proposed to be one of the major post-translational mechanisms responsible for the effects of resveratrol