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Conversely, the quasi-programmed aging theory that focuses on signaling pathways beneficial earlier in life but driving aging later, identifies FOXO factors as gerosuppressors antagonizing chronic hyper-activation of the nutrient-sensing TOR pathway known to accelerate aging [110]

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Data analysis was performed using Clampfit 10.2 software (Molecular Devices), and Mini- Analysis 6.0 software (Synaptosoft Inc

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