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The occurrence of hyperactivated platelets and fibrinaloid microclots in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)

Throughout the manuscript, rejuvenation-oriented terminology has been avoided in favor of functional descriptors that more accurately reflect the current evidence base, including circadian robustness, rhythm amplitude, sleep consolidation, and metabolic alignment

It also has been shown to provide a platform for CD44 oligomerization and coupling to adaptor proteins, receptor tyrosine kinases (RTKs) or nonreceptor protein-tyrosine kinases for consequent CD44 activation and signaling (Sun et al., 2020)