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Berberine suppresses colonic inflammation in dextran sulfate sodiuminduced murine colitis through inhibition of cytosolic phospholipase A2 activity

A recent systematic review and meta-analysis of 25 observational studies found proton-pump inhibitor use was associated with a small increased risk of vitamin B 12 deficiency

1) Many of these GI diseases have limited therapeutic options, particularly when first-line therapies are unsuccessful, a gap which elemental nutrition therapy may be able to fill as an adjunct or stand-alone therapeutic and nutritional intervention

Therefore, standardizing protocols for QA/QC in toxico-metabolomics is crucial for improving the quality and reproducibility of data in this type of studies, and to facilitate the joint analysis and re-use of data from different studies and sources