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We monitor PubMed for new peer-reviewed studies on this topic and email a short summary when something meaningful changes.

Prolonged overdose of B6 (150-200 mg/day) over weeks can cause severe sensory-nervous-system dysfunction and ataxia.37 With normal usage serious adverse effects are not reported for pyridoxine (vitamin B6), however, diarrhoea, emesis and rosacea-like dermatitis may be observed in some cases (38)

Its ability to regulate magnesium movement, support musculoskeletal health, and influence nervous system function highlights its potential therapeutic benefits for individuals experiencing magnesium abnormalities

Gut issues IBS, leaky gut, NSAID-related GI damage, and chronic intestinal inflammation