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There is no control group (patients receiving a placebo), no randomisation, and selection criteria may introduce bias

In an in vivo study, the cyclophosphamide-induced ICmodel was developed in female rats

2x 35ml bottles - Complete treatment for an intensive 8-12 week cycle Biphasic formula - Combines aqueous phase with liposoluble active ingredients for deep penetration Caffeine - Stimulates lipolysis (fat breakdown) and improves microcirculation Carnitine - Facilitates fatty acid transport and fat burning Organic Silicium Complex - Improves skin elasticity and firmness Centella Asiatica Extract - Anti-inflammatory action and connective tissue remodeling Anti-cellulite effect - Visibly reduces "orange peel" appearance Body reshaping - Improves contour and firmness of treated areas Draining action - Reduces water retention and swelling Improved texture - Smoother, firmer and more elastic skin Fast absorption - Light texture, non-greasy, absorbs instantly Shake bottle well before each use to mix the two phases

Previous evidence has indicated that calcitonin gene-related peptide (CGRP) and cytokines might play a role in the pathogenesis of migraine (159161)