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There is no clinical data on this combination, and it is generally not recommended because the GLP-1 receptor activation from multiple compounds would overlap, potentially increasing gastrointestinal side effects without proportional benefit

[5] This selectivity makes it the preferred GHRP partner for research designs where GH-specific signaling is the goal

WO2013012918A1 - Heterocyclic compounds and uses thereof - Google Patents Heterocyclic compounds and uses thereof Download PDF Info Publication number WO2013012918A1 WO2013012918A1 PCT/US2012/047190 US2012047190W WO2013012918A1 WO 2013012918 A1 WO2013012918 A1 WO 2013012918A1 US 2012047190 W US2012047190 W US 2012047190W WO 2013012918 A1 WO2013012918 A1 WO 2013012918A1 Authority WO WIPO (PCT) Prior art keywords compound formula alkyl substituted heteroaryl Prior art date Legal status (The legal status is an assumption and is not a legal conclusion

the program filters out sequences based on the number of times they appear in the relevant reference genome