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Curcumin also has antiangiogenic properties, inhibiting stromal derived factor-1 (SDF-1), which is associated with abnormal blood vessel growth in the retina

The same study showed a similar effect in cases of organoids, patient derived xenografts as well as colorectal cancer cell lines ( FIGURE 3 TGF- Signaling Pathway The interplay between TGF- and Wnt pathways is context-dependent and can result in different outcomes