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Storkebaum E, Carmeliet P (2004) VEGF: a critical player in neurodegeneration

This highlights the necessity of proactive screening and early intervention to prevent the progression of these complications [39]

Analysis of the data indicates that short-term treatment with RM-493 increased resting energy expenditure significantly (by 6.4% vs placebo), thus suggesting RM-493 may be clinically effective for treating obesity