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Dr Laura Geige Medical Director and Senior Aesthetics Practitioner at Its Me & You Clinic, with a professional background in dentistry, medical aesthetics and cosmetic dermatology

(PubMed) Fan H, Han X, Shang X, et al

Finally, none of these studies included intention-to-treat analysis, blinding or sample size calculation, which may have introduced bias in their statistical analysis (Vidal-Alaball et al., 2004