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The ability to conduct longitudinal studies assaying metabolic changes simultaneously in the brain tissue and the periphery represents an outstanding advantage of mouse models to define the relationship between preclinical biomarkers of AD vs clinical signatures

However, these measures are susceptible to interpretive bias and fail to accurately capture dynamic fatigue states, which may undermine data reliability [186, 187]

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Nutrition care in cancer surgery patients: a narrative review of nutritional screening and assessment methods and nutritional considerations