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Sikiric et al., 1997b

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This immuno-protective tissue guards against foreign antigens and pathogens from anything we consume orally

Clinically, melatonin has been reported to reduce the risk of hemorrhagic transformation after tissue plasminogen activator (t-PA) therapy in ischemic stroke (150, 151), suggesting a potential role in improving thrombolytic safety through modulation of BBB permeability