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surfactants suitable for use in combination with the organic dry cleaning solvent as adjuncts are well known in the art, being described in more detail in Kirk Othmer's Encyclopaedia of Chemical Technology, 3rd Ed., Vol

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Given that limited capacity of self-renewal in neurons (Sorrells et al., 2018), targeting neuronal death by neuroprotection holds promise in neurological disease therapy (Neuhaus et al., 2017)

Followed by intravenous administration, their technique is able to overcome the poor intracerebral availability of the drug and enhanced PFS in patients with recurrent GBMs