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Description

CPL500036 selectively inhibits phosphodiesterase (PDE) 10A, an enzyme almost exclusively expressed in the medium spiny neurons of the striatum

Recruitment of adenomatous polyposis coli and beta-catenin to axin-puncta

Therefore, microglia can quickly react and respond to danger/damage signals in a complex manner that facilitates the destruction and/or removal of these molecules as well as the initiation of subsequent repair and/or immunological resolution