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Iron infusion therapy is especially suitable for patients who cannot tolerate iron supplements, do not absorb iron correctly in the gastrointestinal tract, or have chronic blood loss

At the molecular level, copper directly interacts with A and tau proteins, facilitating their abnormal aggregation, enhancing neurotoxicity, and promoting both A deposition and tau hyperphosphorylation, ultimately leading to neuronal dysfunction and injury (185)

Given the beneficial effects of several precursors and inhibitors summarized above, these strategies may be promising for finding a therapeutic strategy for AD, either as lead molecules or in combination approaches with other classes of molecules or drugs, with several studies having been launched at the clinical level

Garcia ES, Sandwell DT, Smith WH (2014) Retracking Cryosat-2, Envisat and Jason-1 radar altimetry waveforms for improved gravity field recovery