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Additionally, we explained that it could be difficult for the CMS Innovation Center to conduct a viable test of a specialty or disease-specific model, if we were to require that beneficiaries who previously designated an ACO professional as their primary clinician remain assigned to the Shared Savings Program ACO under all circumstances

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These studies indicate that hGS is a homodimer of 52 kDa subunit molecular weight and it shares amino acid sequence identity of between 35 and 89% with the other eukaryotic enzymes (Whitbread et al ., 1998), whereas there is no detectable sequence similarity between the eukaryotic enzymes and their bacterial counterpart

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