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71401141010.1097/00002030-199311000-00001 AIDS 11 MillmanA

Although their protective role in cardiovascular and neurological diseases is clear, their role in cancer remains controversial: Different PRDX isoforms may have a tumor-suppressor or an oncogenic role, depending on the cancer type

After sonication (2 pulses of 5 s at 4 C), the cell debris was separated by centrifugation at 1000 g for 10 min, and the supernatant was ultracentrifuged at 80,000 g for 30 min at 4 C