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There is a need for precision diagnostics that reflect all relevant symptoms, are more effective at predicting prognosis including for fertility and cardiovascular risks, and potentially indicate physiological pathways relevant to the syndrome

(2021) highlighted that enzymes secreted by different strains (e.g., Aspergillus niger and Thermoascus aurantiacus ), such as endo-xylanases and -glucanases, exhibited significantly varied hydrolysis efficiencies toward non-starch polysaccharides (e.g., arabinoxylan and -glucan), directly impacting polysaccharide extraction yields and product composition