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This increases the oxidative burden in the body because of the excessive amounts of oxidized glutathione waiting to be recharged by antioxidants

The sensor fluorescence response was measured over a time course and an oxygen ramping script mode together with the ACU was used to apply an oxygen gradient by flushing the measurement chamber with nitrogen gas (99.998 % v/v, Westfalen AG, Mnster, Germany)

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Chemosensitivity of patient-derived cancer stem cells identifies colorectal cancer patients with potential benefit from FGFR inhibitor therapy