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3 , e290 (2012)

Extracellular accumulation of nitric oxide, hydrogen peroxide, and glutamate in astrocytic cultures following glutathione depletion, complex I inhibition, and/or lipopolysaccharide-induced activation

Likewise, luteolin seems to inhibit TNF--induced IL-8 production in this cell line through blockade in the phosphorylation of MAPKs, following IkappaB degradation and NF-kappaB activation [96] Also, in RAW264.7 cells, luteolin acts as an antagonist of the IKK/ by blocking its phosphorylation and the action of NF-B [97]

Benzyl isothiocyanate inhibits prostate cancer development in the transgenic adenocarcinoma mouse prostate (TRAMP) model, which is associated with the induction of cell cycle G1 arrest