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Description

In addition, cysteine residues can be post-translationally modified by forming a mixed disulfide with glutathione ( S -glutathionylation), which protects thiol groups from further oxidation and can influence protein activity

10.1186/1479-5876-12-32 J Transl Med

Abstract The nuclear factor erythroid 2-related factor 2 (Nrf2) is a key regulator of cellular defense against oxidative stress and correlated with classical toxicological endpoints