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Aripiprazole exposure was similar for deltoid and gluteal intramuscular injections of 441 mg ARISTADA, thus are interchangeable

10.1162/jocn.2009.21193 156 DigbyL

Hence, with the permeability in the blood-brain barrier and the vulnerability to the hyperammonemic and inflammatory environment, low-grade edema and oxidative/nitrosative stress are produced, with astrocytic dysfunction.71 New therapeutic targetsManganese-chelating agents Based on the evidence suggesting the involvement of manganese in the death of dopaminergic cells and its accumulation reported in the brain tissue of cirrhotic patients, it is not illogical to think that manganese chelators could aid in lowering the rates of parkinsonism associated with cirrhosis and in reducing the expression of oxidative stress radicals produced by their interaction with the microglia