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Lipidomic analysis revealed that GSH depletion significantly decreased levels of neutral lipids, including diacylglycerols (DAGs), triacylglycerols (TAGs), and cholesterol esters (CEs), while GSH depletion increased levels of sphingolipids and phospholipids (Figure 4, B and C, and Supplemental Figure 3, AC), many of which have been shown to improve hepatic steatosis (26)