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However, comprehensive guidelines on the genetic assessment of these pathologies are lacking, while on the other hand, the constantly evolving genetic tests may not be enough to provide a definitive result [72]

In another study, when comparing T1D C-peptide positive pre-pubertal children and adults vs their C-peptide negative counterparts, patients with a residual -cell function had higher IGF-I levels despite similar glycemic control (47, 48)

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