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Currently NAC has the most evidence of having a beneficial effect as an adjuvant agent in the negative symptoms of schizophrenia, severe autism, depression, and obsessive compulsive and related disorders. (13) For example a large RCT of 140 participants observed significant improvements on global symptomatology, and general and negative symptoms of schizophrenia in the NAC supplementation (2 g/d

doi: 10.1016/j.clnu.2020.01.005 393 LeisRde CastroMJde LamasCPicnsRCouceML

Results L585 substitution of albumin to a non-aliphatic amino acid weakens FcRn binding The C-terminal DIII of human albumin harbors the primary binding site for human FcRn (Fig