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Annu Rev Pathol 11:451496

This surprising discovery revealed a new pathway for mitochondrial signaling and systemic cellular communication

After 48 h, cells were stimulated with 50 ng/mM PMA and 1 g/mL ionomycin, followed by 3 h incubation with GolgiStop to evaluate intracellular cytokine secretion

Nanoparticles show various applications in the biomedical field such as drug and gene delivery, bio-detection of pathogens, detection of proteins, tissue engineering, probing of DNA structure, separation, and purification of biological molecules, tumor destruction via heating and phagokinetic studies [7]